The therapeutic efficacy of propranolol in children with recurrent primary epistaxis
نویسندگان
چکیده
We hypothesized that some characteristics of beta-blockers, including negative inotropic, peripheral vasoconstrictor, and antiangiogenic effects, might be potentially useful in treating children with epistaxis. From June 2010 to March 2012, a total of seven children with recurrent primary epistaxis resistant to conventional management were observed at our institution. An overall effectiveness of propranolol was noted in all seven children when given a dose of 1.5-2 mg/kg/day (divided into three doses) as a second line therapy for terminating epistaxis. Based on our first experience, we believe that propranolol could be a favorable treatment option for patients with primary epistaxis.
منابع مشابه
A comparative study of propranolol versus silver nitrate cautery in the treatment of recurrent primary epistaxis in children
BACKGROUND Epistaxis is a common medical problem in pediatric population. Although in most cases it is mild and self-limiting, a proportion of childhood epistaxis is massive, recurrent, or resistant to conventional management. OBJECTIVE To compare effectiveness of propranolol as a treatment option for childhood epistaxis versus conventional silver nitrate cautery. STUDY DESIGN AND METHODOLO...
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